Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Client:
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Client:
Project Goal
Project Goal
Project Goal
Project Goal
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Glioblastoma Cells
Glioblastoma Cells
Glioblastoma Cells
Injection of AAV vector into tumor
Injection of AAV vector into tumor
Injection of AAV vector into tumor
SSE elements of the construct interact with the cellular transcription factors
SSE elements of the construct interact with the cellular transcription factors
SSE elements of the construct interact with the cellular transcription factors
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
Destruction of cancer cells via effector T-cells and macrophages
Destruction of cancer cells via effector T-cells and macrophages
Destruction of cancer cells via effector T-cells and macrophages
Genetic material inside the AAV Vector
Genetic material inside the AAV Vector
Genetic material inside the AAV Vector
Interleukin - 12
Interleukin - 12
Interleukin - 12
The Process
The Process
The Process
The Process
Animation type:
Animation type:
Animation type:
3D + High-End 3D
3D + High-End 3D
3D + High-End 3D
Project timline:
Project timline:
Project timline:
8 weeks
8 weeks
8 weeks
Review:
Review:
Review:
5 zoom calls + 5 e-mail feedback sessions
5 zoom calls + 5 e-mail feedback sessions
5 zoom calls + 5 e-mail feedback sessions
Find out which of our 26 scientific animation options works best for investor relations and communications:
Find out which of our 26 scientific animation options works best for investor relations and communications:
Find out which of our 26 scientific animation options works best for investor relations and communications:
To ensure scientific accuracy while maintaining production efficiency, we employed a combination of Deck 3D and High-end 3D styles. A precisely modeled protein-DNA interactions and AAV capsids with accurate genome packaging ensured fidelity of visualizations. Extensive scientific discussions with the client helped refine the depiction of immune cell behavior, cancer cell morphology, and tissue interactions.
To clearly communicate the therapy’s mechanism of action, we used a split-screen approach that simultaneously presented macroscopic and molecular perspectives. This layered narrative illustrated how the therapy selectively activates genes in cancer cells, triggering a targeted immune response while sparing healthy tissue.
Broad Visualization: Deck 3D was used to establish the brain model and tumor integration.
Molecular Accuracy: High-end modeling ensured precise representation of viral vectors and gene activation.
Split-Screen Perspective: Simultaneous macro- and micro-scale views clarified the treatment process.
Mechanism of Action: SSE activation and pro-drug conversion were depicted with clarity and scientific rigor.
Why did we use this
animation type?
Why did we use this
animation type?
Why did we use this
animation type?
The complexity of Trogenix’s therapy required a hybrid approach often needed for scientific animations that combine static 3D, dynamic molecular animation, and layered visual cues. By using pre-existing, scientifically accurate 3D assets—such as brain models based on 10-tesla MRI scans—we accelerated production without compromising accuracy. This approach effectively communicated the therapy’s novel mechanism while addressing challenges such as visualizing complex molecular interactions for a broad audience and meeting strict scientific standards.
We met tight production timelines by leveraging high-accuracy models from our library, employing a split-screen layout to present both macro-level processes and molecular mechanisms, and ensuring consistent branding in alignment with Trogenix’s established guidelines.
Outcome:
Outcome:
Outcome:
The final animation successfully conveyed the intricate scientific concepts underlying Trogenix’s Odysseus platform in a clear and engaging manner. By balancing detail with accessibility, the project met both investor communication objectives and the needs of scientific communication for biotech, demonstrating the flexibility of our production process to adapt to the needs of early-stage biotech companies, tight timelines, and complex scientific storytelling.
The client leveraged the animation for investor relations, website presentations, and industry discussions. Our team delivered a high-quality visualization that adhered to the client’s brand guidelines while meeting the highest standards of scientific accuracy. This project also highlights our ability to seamlessly integrate existing scientific models, significantly reducing production time while maintaining rigorous accuracy—an approach that consistently delivers value for both early-stage biotech companies and large pharmaceutical organizations.
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Full animation
Full animation
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Case Study Animation
Case Study Animation
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“Fantastic team to partner with throughout the entire process. Excellent output and management!”
"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"
“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.
“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”
“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”
“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."
“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”
"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"
“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”
"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."
"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."
"Excellent work by the Visual Science team!"
"Excellent work and project management."
"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."
"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."
"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."
"Very responsive and efficient. Thank you!"
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Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor,
New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor, New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor,
New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
