Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Platform MoA Animation: Synthetic Super-Enhancers
Client:


Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Trogenix is a biotechnology company developing gene therapies. Its Odysseus platform uses synthetic super-enhancers (SSEs) to selectively activate therapeutic genes in diseased cells while minimizing harm to healthy tissue. This innovative approach targets glioblastoma by leveraging tumor-specific transcription factors (TFs) to trigger treatment exclusively in malignant cells. By both destroying tumors and stimulating an immune response, Odysseus represents a promising advancement in brain cancer therapy.
Client:



Project Goal
Project Goal
Project Goal
Project Goal
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.
Trogenix approached our team to create a 3D animation that visually communicates the mechanism of action (MoA) behind the Odysseus platform. The animation needed to break down the complex molecular and cellular processes involved in the therapy, making them accessible and engaging for investors, researchers, and industry stakeholders. The final animation serves as a key tool in Trogenix’s outreach efforts, helping to illustrate the scientific foundation and therapeutic potential of its novel gene therapy.
See full animation.




Glioblastoma Cells
Glioblastoma Cells
Glioblastoma Cells
Glioblastoma Cells
Injection of AAV vector into tumor
Injection of AAV vector into tumor
Injection of AAV vector into tumor
Injection of AAV vector into tumor




SSE elements of the construct interact with the cellular transcription factors
SSE elements of the construct interact with the cellular transcription factors
SSE elements of the construct interact with the cellular transcription factors
SSE elements of the construct interact with the cellular transcription factors
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”
“Beyond the beautifully crafted animations, behind the scenes, its remarkable how quickly the team picked up the science to create an accurate model with minimal input. The design process was very efficient, responsive, and well managed.”



Chief Executive Officer at Trogenix




Destruction of cancer cells via effector T-cells and macrophages
Destruction of cancer cells via effector T-cells and macrophages
Destruction of cancer cells via effector T-cells and macrophages
Destruction of cancer cells via effector T-cells and macrophages




Genetic material inside the AAV Vector
Genetic material inside the AAV Vector
Genetic material inside the AAV Vector
Genetic material inside the AAV Vector
Interleukin - 12
Interleukin - 12
Interleukin - 12
Interleukin - 12
The Process
The Process
The Process
The Process
Animation type:
Animation type:
Animation type:
Animation type:
3D + High End 3D
3D + High End 3D
3D + High End 3D
3D + High End 3D
Project timline:
Project timline:
Project timline:
Project timline:
8 weeks
8 weeks
8 weeks
8 weeks
Review:
Review:
Review:
Review:
5 zoom calls + 7 e-mail feedback sessions
5 zoom calls + 7 e-mail feedback sessions
5 zoom calls + 7 e-mail feedback sessions
5 zoom calls + 7 e-mail feedback sessions
Team:











Find out which of our 26 scientific animation options works best for investor relations and communications:
Find out which of our 26 scientific animation options works best for investor relations and communications:
Find out which of our 26 scientific animation options works best for investor relations and communications:
Find out which of our 26 scientific animation options works best for investor relations and communications:
To ensure scientific accuracy while maintaining production efficiency, we employed a combination of Deck 3D and High-end 3D styles. A precisely modeled protein-DNA interactions and AAV capsids with accurate genome packaging ensured fidelity of visualizations. Extensive scientific discussions with the client helped refine the depiction of immune cell behavior, cancer cell morphology, and tissue interactions.
To clearly communicate the therapy’s mechanism of action, we used a split-screen approach that simultaneously presented macroscopic and molecular perspectives. This layered narrative illustrated how the therapy selectively activates genes in cancer cells, triggering a targeted immune response while sparing healthy tissue.
Broad Visualization: Deck 3D was used to establish the brain model and tumor integration.
Molecular Accuracy: High-end modeling ensured precise representation of viral vectors and gene activation.
Split-Screen Perspective: Simultaneous macro- and micro-scale views clarified the treatment process.
Mechanism of Action: SSE activation and pro-drug conversion were depicted with clarity and scientific rigor.
Why did we use this
animation type?
Why did we use this
animation type?
Why did we use this
animation type?
Why did we use this
animation type?
The complexity of Trogenix’s therapy required a hybrid approach that combined static 3D, dynamic molecular animation, and layered visual cues. By using pre-existing, scientifically accurate 3D assets—such as brain models based on 10-tesla MRI scans—we accelerated production without compromising accuracy. This approach effectively communicated the therapy’s novel mechanism while addressing challenges such as visualizing complex molecular interactions for a broad audience and meeting strict scientific standards.
We met tight production timelines by leveraging high-accuracy models from our library, employing a split-screen layout to present both macro-level processes and molecular mechanisms, and ensuring consistent branding in alignment with Trogenix’s established guidelines.
Outcome:
Outcome:
Outcome:
Outcome:
The final animation successfully conveyed the intricate scientific concepts underlying Trogenix’s Odysseus platform in a clear and engaging manner. By balancing detail with accessibility, the project met both scientific and investor communication objectives, demonstrating the flexibility of our production process to adapt to the needs of early-stage biotech companies, tight timelines, and complex scientific storytelling.
The client leveraged the animation for investor relations, website presentations, and industry discussions. Our team delivered a high-quality visualization that adhered to the client’s brand guidelines while meeting the highest standards of scientific accuracy. This project also highlights our ability to seamlessly integrate existing scientific models, significantly reducing production time while maintaining rigorous accuracy—an approach that consistently delivers value for both early-stage biotech companies and large pharmaceutical organizations.
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

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Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

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The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

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We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

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Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

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The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

Science Content Lead, Dewpoint Tx
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

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Sr. Comms & IR Associate, Candel Tx
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We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

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CEO, Atsena Therapeutics
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Program Manager, American Chemical Society
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

CEO, Apton Biosystems
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“
Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

VP, Head of Communications, Scorpion Tx
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The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

Science Content Lead, Dewpoint Tx
9/10
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Vice President, R&D, Unicycive Tx
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We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

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CEO, UNITY Biotechnology
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Sr. Comms & IR Associate, Candel Tx
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“
We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

President & CEO, ROME Tx
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“
Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

VP, Corp Dev, Revolution Medicines
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We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

CEO, Atsena Therapeutics
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“
The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Program Manager, American Chemical Society
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

CEO, Apton Biosystems
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“
Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

VP, Head of Communications, Scorpion Tx
7/10
“
The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

Science Content Lead, Dewpoint Tx
9/10
“
I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Vice President, R&D, Unicycive Tx
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We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

CSO, Enterin
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The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

CEO, UNITY Biotechnology
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Beautiful work that is detailed and thoughtful. Great final output.”

Sr. Comms & IR Associate, Candel Tx
10/10
“
We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

President & CEO, ROME Tx
10/10
“
Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

VP, Corp Dev, Revolution Medicines
10/10
“
We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

CEO, Atsena Therapeutics
10/10
“
The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Program Manager, American Chemical Society
10/10
“
Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

CEO, Apton Biosystems
9/10
“
Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

VP, Head of Communications, Scorpion Tx
7/10
“
The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

Science Content Lead, Dewpoint Tx
9/10
“
I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Vice President, R&D, Unicycive Tx
10/10
“
We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

CSO, Enterin
10/10
“
The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

CEO, UNITY Biotechnology
10/10
“
Beautiful work that is detailed and thoughtful. Great final output.”

Sr. Comms & IR Associate, Candel Tx
10/10
“
We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

President & CEO, ROME Tx
10/10
“
Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

VP, Corp Dev, Revolution Medicines
10/10
“
We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

CEO, Atsena Therapeutics
10/10
“
The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Program Manager, American Chemical Society
10/10
“
Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

CEO, Apton Biosystems
9/10
“
Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

VP, Head of Communications, Scorpion Tx
7/10
“
The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”

Science Content Lead, Dewpoint Tx
9/10
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

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10/10
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We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

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The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

CEO, UNITY Biotechnology
10/10
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Beautiful work that is detailed and thoughtful. Great final output.”

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10/10
“
We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”

President & CEO, ROME Tx
10/10
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Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

VP, Corp Dev, Revolution Medicines
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Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.







