RAS(ON) Inhibitors MoA Animation

Client:

Revolution Medicines logo
Revolution Medicines logo

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.

NAS: RVMD

NAS: RVMD

Client:

Revolution Medicines logo
Revolution Medicines logo

Project Goal

Create a short MoA animation about the RAS(ON) imhibitors that remodel the structure of cyclophilin A to create a neomorphic interface with high affinity to KRAS.

Cancer cells in the tissue
Cancer cells in the tissue
Cancer cells in the tissue
Cancer cells in the tissue

Cancer cells in the tissue

RAS-RAF-MEK cascade interactions

RAS(ON) attached to the membrane
RAS(ON) attached to the membrane
RAS(ON) attached to the membrane
RAS(ON) attached to the membrane

RAS(ON) attached to the membrane

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

Bob Nichols photo
Bob Nichols photo
Bob Nichols photo

Vice President, Corporate Development

at REVOLUTION Medicines

Infographics showing basic statistics on RAS mutations in cancer with molecular graphics on background
Infographics showing basic statistics on RAS mutations in cancer with molecular graphics on background
Infographics showing basic statistics on RAS mutations in cancer with molecular graphics on background
Infographics showing basic statistics on RAS mutations in cancer with molecular graphics on background

RAS cancer basic statistics

3D render of cancer cells in normal tissue
3D render of cancer cells in normal tissue
3D render of cancer cells in normal tissue
3D render of cancer cells in normal tissue

Cancer cells

Inhibitory tri-complex formation

The Process

Animation type:

3D/High-end 3D + 2D

Project timline:

7 weeks

Review:

4 zoom calls + 7 e-mail feedback sessions

Team:

Find out which of our 26 scientific animation options works best for investor relations and communications:

While we were producing this animation, our client was updating their brand identity and website, which required ongoing coordination with a separate design team responsible for developing the new company look. Our color scheme and visual style were aligned with the updated brand guidelines and integrated seamlessly into the new design. This was not our first project for Revolution Medicines, so we were able to leverage previously developed assets to support production. However, we refined and improved those models and placed them within a more complex cellular context.

Why did we use this
animation type?

This animation was created in our main 3D style; however, for the interactions within the RAS–RAF cascade, we employed several computational molecular modeling techniques, introducing high-end 3D style elements into the final animation.

We also included a scene featuring animated 2D infographics to present RAS cancer statistics and reinforce the significance of our client’s approach. In short animations, a combination of accurate, eye-catching 3D visuals and informative 2D graphics is often the most effective way to tell a compelling story.

Full animation

Contact us

Contact us

Contact us

Contact us

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor, New York, NY 10281, USA

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science Logo
Visual Science Logo
Visual Science Logo