Visualizing IL-18-based Immune Modulation Therapy MoA
Client:
Fuse Biotherapeutics is a biotechnology company focused on developing immune-modulating therapeutics for cancer treatment, leveraging signaling molecules and multifunctional antibody domains to enhance the body’s natural immune response. Their research centers on cytokine-based therapies, particularly IL-18, which plays a critical role in immune system activation.
Fuse Biotherapeutics is a biotechnology company focused on developing immune-modulating therapeutics for cancer treatment, leveraging signaling molecules and multifunctional antibody domains to enhance the body’s natural immune response. Their research centers on cytokine-based therapies, particularly IL-18, which plays a critical role in immune system activation.
Client:
Project Goal
Project Goal
Fuse Bio required a mechanism of action (MoA) animation to effectively communicate the key advantages of their IL-18-based technology to investors and potential partners. As an early-stage company with limited resources, they needed a cost-effective yet scientifically rigorous approach to maximize impact.
To address these needs, we developed a concise 60-second animation that balanced scientific accuracy with production efficiency. The animation needed to be visually compelling, precise, and easy to understand, particularly for investors who may not have deep scientific expertise.
See full animation.
Fuse Bio required a mechanism of action (MoA) animation to effectively communicate the key advantages of their IL-18-based technology to investors and potential partners. As an early-stage company with limited resources, they needed a cost-effective yet scientifically rigorous approach to maximize impact.
To address these needs, we developed a concise 60-second animation that balanced scientific accuracy with production efficiency. The animation needed to be visually compelling, precise, and easy to understand, particularly for investors who may not have deep scientific expertise.
See full animation.
Fuse Bio required a mechanism of action (MoA) animation to effectively communicate the key advantages of their IL-18-based technology to investors and potential partners. As an early-stage company with limited resources, they needed a cost-effective yet scientifically rigorous approach to maximize impact.
To address these needs, we developed a concise 60-second animation that balanced scientific accuracy with production efficiency. The animation needed to be visually compelling, precise, and easy to understand, particularly for investors who may not have deep scientific expertise.
See full animation.
Activated T-Cell targeting diseased cell
Activated T-Cell targeting diseased cell
Interleukin-18 and IL-18 Binding Protein
Interleukin-18 and IL-18 Binding Protein
IL-18 and Attenuator
IL-18 and Attenuator
"Visual Science transformed our complex mechanism of action into a visually compelling story that exceeded our expectations. The attention to detail, creativity, and their ability to simplify and enhance our narrative visually was truly remarkable.
They demonstrated a deep understanding of our needs and a commitment to excellence throughout the process."
"Visual Science transformed our complex mechanism of action into a visually compelling story that exceeded our expectations. The attention to detail, creativity, and their ability to simplify and enhance our narrative visually was truly remarkable.
They demonstrated a deep understanding of our needs and a commitment to excellence throughout the process."
"Visual Science transformed our complex mechanism of action into a visually compelling story that exceeded our expectations. The attention to detail, creativity, and their ability to simplify and enhance our narrative visually was truly remarkable.
They demonstrated a deep understanding of our needs and a commitment to excellence throughout the process."
"Visual Science transformed our complex mechanism of action into a visually compelling story that exceeded our expectations. The attention to detail, creativity, and their ability to simplify and enhance our narrative visually was truly remarkable.
They demonstrated a deep understanding of our needs and a commitment to excellence throughout the process."
Co-Founder and CEO at Fuse Biotherapeutics
Co-Founder and CEO at Fuse Biotherapeutics
IL-18 binding to receptors triggering unsafe signaling
IL-18 binding to receptors triggering unsafe signaling
IL-18 and Fuse Bios' Attenuator
IL-18 and Fuse Bios' Attenuator
Antibody Domain bringing IL-18 to Immune Cells
Antibody Domain bringing IL-18 to Immune Cells
The Process
The Process
Animation type:
Deck 3D + High-end 3D elements
Project timline:
7 weeks
Review:
4 zoom calls + 5 e-mail feedback sessions
Find out which of our 26 scientific animation options works best for investor relations and communications:
Given the company’s early-stage status, the production process needed to be optimized for both speed and cost efficiency while maintaining the highest scientific standards. We structured the animation using a hybrid approach, selecting the most effective animation style for each scene:
DECK 3D for Introduction and Context: The opening scenes utilized DECK 3D animation, in which molecular structures remained scientifically accurate while the animation itself was less dynamic. This approach enabled faster production while keeping costs under control—key considerations for a startup operating under tight budget and timeline constraints.
Molecular Dynamics Simulation: While DECK 3D was used for parts of the animation, certain scenes required more detailed molecular interactions. These were enhanced with molecular dynamics simulations to ensure precise representation of molecular behavior and interactions.
2D Overlays for Clarity: Because the audience included investors without deep technical backgrounds, we implemented a dual-layered visualization approach. Alongside the 3D molecular animation sequences, we incorporated simplified 2D schematic overlays that mirrored key molecular processes in real time. These 2D callouts and structural highlights helped break down complex mechanisms and modifications, making them more accessible without compromising scientific accuracy.
Why did we use this
animation type?
Why did we use this
animation type?
This hybrid visual approach significantly improved the clarity of the animation, ensuring that viewers could both appreciate the molecular-level accuracy and easily follow the process. The client valued this balance, as it reinforced confidence in the scientific integrity of the animation while keeping it engaging and accessible to a broader audience. The animation was successfully delivered within six weeks, meeting the client’s tight deadlines for investor communications.
Outcome:
The final MoA animation effectively conveyed Fuse Biotherapeutics’ IL-18 technology, balancing scientific rigor with accessibility. By tailoring the animation workflow to the company’s strategic needs, the production successfully communicated the core mechanism to both technical experts and investors. The project demonstrated how flexible production choices can enhance scientific storytelling while accommodating strict timeframes and budget constraints. Fuse Biotherapeutics praised the animation for its engaging and digestible presentation, underscoring the impact of clear and compelling scientific visualization for medical & scientific communication services.
Full animation
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“Fantastic team to partner with throughout the entire process. Excellent output and management!”
"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"
“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.
“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”
“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”
“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."
“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”
"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"
“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”
"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."
"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."
"Excellent work by the Visual Science team!"
"Excellent work and project management."
"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."
"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."
"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."
"Very responsive and efficient. Thank you!"
Contact us
“Fantastic team to partner with throughout the entire process. Excellent output and management!”
"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"
“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.
“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”
“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”
“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."
“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”
"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"
“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”
"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."
"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."
"Excellent work by the Visual Science team!"
"Excellent work and project management."
"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."
"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."
"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."
"Very responsive and efficient. Thank you!"
Contact us
Contact us
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor,
New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor,
New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor, New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
Contacts
Address
200 Vesey Street, 24th floor,
New York, NY 10281, USA
© 2026, Visual Science. All rights reserved.
