Atopic Dermatitis Antibody Combination Treatment APG279
Atopic Dermatitis Antibody Combination Treatment APG279
Atopic Dermatitis Treatment with APG777
and APG990
Atopic Dermatitis Antibody Combination Treatment APG279
Client:
Client:
Client:
Client:
Apogee Therapeutics is a clinical-stage biotechnology company that discovers and develops novel therapies for a range of inflammatory and immunological diseases. The company seeks to achieve this by focusing on established biologic drivers of disease and applying advanced antibody engineering to create product candidates with optimized properties that may overcome the limitations of existing therapies.
Apogee Therapeutics is a clinical-stage biotechnology company that discovers and develops novel therapies for a range of inflammatory and immunological diseases. The company seeks to achieve this by focusing on established biologic drivers of disease and applying advanced antibody engineering to create product candidates with optimized properties that may overcome the limitations of existing therapies.
Apogee Therapeutics is a clinical-stage biotechnology company that discovers and develops novel therapies for a range of inflammatory and immunological diseases. The company seeks to achieve this by focusing on established biologic drivers of disease and applying advanced antibody engineering to create product candidates with optimized properties that may overcome the limitations of existing therapies.
Apogee Therapeutics is a clinical-stage biotechnology company that discovers and develops novel therapies for a range of inflammatory and immunological diseases. The company seeks to achieve this by focusing on established biologic drivers of disease and applying advanced antibody engineering to create product candidates with optimized properties that may overcome the limitations of existing therapies.
Project Goal
Project Goal
Project Goal
Project Goal
Apogee Therapeutics required a 3D animation to explain the mechanisms of action (MoA) of its monoclonal antibodies, zumilokibart (APG777) and APG990, for the treatment of atopic dermatitis. The animation demonstrated how zumilokibart blocks IL-13 to reduce type 2 inflammation and how APG990 targets the OX40 ligand to modulate the immune response. It also illustrated Apogee’s antibody recycling mechanism, which extends therapeutic half-life. Designed for investors and healthcare professionals, the animation simplified complex biological pathways and highlighted the benefits of Apogee’s treatments.
See full animation.
Apogee Therapeutics required a 3D animation to explain the mechanisms of action (MoA) of its monoclonal antibodies, zumilokibart (APG777) and APG990, for the treatment of atopic dermatitis. The animation demonstrated how zumilokibart blocks IL-13 to reduce type 2 inflammation and how APG990 targets the OX40 ligand to modulate the immune response. It also illustrated Apogee’s antibody recycling mechanism, which extends therapeutic half-life. Designed for investors and healthcare professionals, the animation simplified complex biological pathways and highlighted the benefits of Apogee’s treatments.
See full animation.
Apogee Therapeutics required a 3D animation to explain the mechanisms of action (MoA) of its monoclonal antibodies, zumilokibart (APG777) and APG990, for the treatment of atopic dermatitis. The animation demonstrated how zumilokibart blocks IL-13 to reduce type 2 inflammation and how APG990 targets the OX40 ligand to modulate the immune response. It also illustrated Apogee’s antibody recycling mechanism, which extends therapeutic half-life. Designed for investors and healthcare professionals, the animation simplified complex biological pathways and highlighted the benefits of Apogee’s treatments.
See full animation.
Apogee Therapeutics required a 3D animation to explain the mechanisms of action (MoA) of its monoclonal antibodies, zumilokibart (APG777) and APG990, for the treatment of atopic dermatitis. The animation demonstrated how zumilokibart blocks IL-13 to reduce type 2 inflammation and how APG990 targets the OX40 ligand to modulate the immune response. It also illustrated Apogee’s antibody recycling mechanism, which extends therapeutic half-life. Designed for investors and healthcare professionals, the animation simplified complex biological pathways and highlighted the benefits of Apogee’s treatments.
See full animation.
Antibody molecules: zumilokibart (APG777) and APG990
Antibody molecules: zumilokibart (APG777) and APG990
Antibody molecules: zumilokibart (APG777) and APG990
APG777 internalized by cell
APG777 internalized by cell
APG777 internalized by cell
Atopic Dermatitis
Atopic Dermatitis
Atopic Dermatitis
“Incredible animations that really help bring our science to life. I strongly recommend Visual Science!”
“Incredible animations that really help bring our science to life. I strongly recommend Visual Science!”
“Incredible animations that really help bring our science to life. I strongly recommend Visual Science!”
“Incredible animations that really help bring our science to life. I strongly recommend Visual Science!”
Vice President, Medical Affairs
Epidermis and Dermis are impacted by Atopic dermatitis
Epidermis and Dermis are impacted by Atopic dermatitis
Epidermis and Dermis are impacted by Atopic dermatitis
Zumilokibart binging to IL-13
Zumilokibart binging to IL-13
Zumilokibart binging to IL-13
IL-13 cytokine driving type 2 inflammatory signaling
IL-13 cytokine driving type 2 inflammatory signaling
IL-13 cytokine driving type 2 inflammatory signaling
The Process
The Process
Animation type:
Animation type:
High-End 3D
High-End 3D
Project timline:
Project timline:
5 weeks
5 weeks
Review:
Review:
3 zoom calls + 6 e-mail feedback sessions
3 zoom calls + 6 e-mail feedback sessions
Team:
Find out which of our 26 scientific animation options works best for investor relations and communications:
To bring Apogee Therapeutics’ research to life, we created a high-end 3D animation that visualized the complex molecular mechanisms underlying atopic dermatitis and its treatment with zumilokibart and APG990. Detailed 3D models illustrated skin barrier disruption caused by chronic inflammation, while dynamic molecular animations demonstrated how IL-13 and the OX40 ligand drive disease progression. Split-screen sequences were used throughout the animation to compare inflammatory pathways, treatment mechanisms, and therapeutic outcomes, providing a clear visual distinction between untreated and treated conditions. By leveraging cinematic 3D rendering and precise molecular interactions, we ensured the animation was both scientifically accurate and visually compelling.
High-End 3D Animation: Realistic molecular interactions and detailed skin models.
Molecular Visualization: Clear depiction of IL-13 and OX40 ligand signaling pathways.
Split Screens: Side-by-side comparisons of inflammation, treatment mechanisms, and outcomes.
Therapeutic Impact: Visualization of extended antibody half-life and reduced dosing frequency.
To bring Apogee Therapeutics’ research to life, we created a high-end 3D animation that visualized the complex molecular mechanisms underlying atopic dermatitis and its treatment with zumilokibart and APG990. Detailed 3D models illustrated skin barrier disruption caused by chronic inflammation, while dynamic molecular animations demonstrated how IL-13 and the OX40 ligand drive disease progression. Split-screen sequences were used throughout the animation to compare inflammatory pathways, treatment mechanisms, and therapeutic outcomes, providing a clear visual distinction between untreated and treated conditions. By leveraging cinematic 3D rendering and precise molecular interactions, we ensured the animation was both scientifically accurate and visually compelling.
High-End 3D Animation: Realistic molecular interactions and detailed skin models.
Molecular Visualization: Clear depiction of IL-13 and OX40 ligand signaling pathways.
Split Screens: Side-by-side comparisons of inflammation, treatment mechanisms, and outcomes.
Therapeutic Impact: Visualization of extended antibody half-life and reduced dosing frequency.
Why did we use this
animation type?
Why did we use this
animation type?
A high-end 3D animation was chosen to accurately depict the complex molecular interactions involved in atopic dermatitis and the treatments zumilokibart and APG990. Detailed 3D models of IL-13, OX40, and immune responses provided clarity while explaining intricate biological processes to both scientific and general audiences. The split-screen format enabled clear comparisons of the therapies’ mechanisms, highlighting their complementary roles in targeting type 1, type 2, and type 3 inflammation.
A high-end 3D animation was chosen to accurately depict the complex molecular interactions involved in atopic dermatitis and the treatments zumilokibart and APG990. Detailed 3D models of IL-13, OX40, and immune responses provided clarity while explaining intricate biological processes to both scientific and general audiences. The split-screen format enabled clear comparisons of the therapies’ mechanisms, highlighting their complementary roles in targeting type 1, type 2, and type 3 inflammation.
A high-end 3D animation was chosen to accurately depict the complex molecular interactions involved in atopic dermatitis and the treatments zumilokibart and APG990. Detailed 3D models of IL-13, OX40, and immune responses provided clarity while explaining intricate biological processes to both scientific and general audiences. The split-screen format enabled clear comparisons of the therapies’ mechanisms, highlighting their complementary roles in targeting type 1, type 2, and type 3 inflammation.
A high-end 3D animation was chosen to accurately depict the complex molecular interactions involved in atopic dermatitis and the treatments zumilokibart and APG990. Detailed 3D models of IL-13, OX40, and immune responses provided clarity while explaining intricate biological processes to both scientific and general audiences. The split-screen format enabled clear comparisons of the therapies’ mechanisms, highlighting their complementary roles in targeting type 1, type 2, and type 3 inflammation.
Outcome:
Outcome:
The final animation clearly conveyed the mechanisms of action of zumilokibart and APG990 in the treatment of atopic dermatitis. It simplified complex immune responses and showcased the therapies’ potential for long-lasting symptom relief with less frequent dosing. The animation successfully supported investor communications, educational outreach, and scientific presentations, positioning the drugs as promising solutions for chronic inflammatory diseases.
The final animation clearly conveyed the mechanisms of action of zumilokibart and APG990 in the treatment of atopic dermatitis. It simplified complex immune responses and showcased the therapies’ potential for long-lasting symptom relief with less frequent dosing. The animation successfully supported investor communications, educational outreach, and scientific presentations, positioning the drugs as promising solutions for chronic inflammatory diseases.
The final animation clearly conveyed the mechanisms of action of zumilokibart and APG990 in the treatment of atopic dermatitis. It simplified complex immune responses and showcased the therapies’ potential for long-lasting symptom relief with less frequent dosing. The animation successfully supported investor communications, educational outreach, and scientific presentations, positioning the drugs as promising solutions for chronic inflammatory diseases.
The final animation clearly conveyed the mechanisms of action of zumilokibart and APG990 in the treatment of atopic dermatitis. It simplified complex immune responses and showcased the therapies’ potential for long-lasting symptom relief with less frequent dosing. The animation successfully supported investor communications, educational outreach, and scientific presentations, positioning the drugs as promising solutions for chronic inflammatory diseases.
Full animation
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CEO, Atsena Therapeutics
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
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Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
