TARA-002:
Cell-Based Therapy for Bladder Cancer MoA

TARA-002:
Cell-Based Therapy for Bladder Cancer MoA

TARA-002:
Cell-Based Therapy for Bladder Cancer MoA

TARA-002:
Cell-Based Therapy for Bladder Cancer MoA

Client:

Protara Therapeutics logo
Protara Therapeutics logo

Protara Therapeutics is a biotechnology company focused on developing therapies for cancer and rare diseases. Its lead candidate, TARA-002, is a cell-based therapy for non–muscle-invasive bladder cancer (NMIBC) and lymphatic malformations (LMs) and has shown promising clinical trial results. Protara approached our team to create an animation that would clearly communicate the science behind TARA-002, illustrating its mechanism of action and potential benefits for healthcare professionals and patients.

Protara Therapeutics is a biotechnology company focused on developing therapies for cancer and rare diseases. Its lead candidate, TARA-002, is a cell-based therapy for non–muscle-invasive bladder cancer (NMIBC) and lymphatic malformations (LMs) and has shown promising clinical trial results. Protara approached our team to create an animation that would clearly communicate the science behind TARA-002, illustrating its mechanism of action and potential benefits for healthcare professionals and patients.

Protara Therapeutics is a biotechnology company focused on developing therapies for cancer and rare diseases. Its lead candidate, TARA-002, is a cell-based therapy for non–muscle-invasive bladder cancer (NMIBC) and lymphatic malformations (LMs) and has shown promising clinical trial results. Protara approached our team to create an animation that would clearly communicate the science behind TARA-002, illustrating its mechanism of action and potential benefits for healthcare professionals and patients.

Client:

Project Goal

Project Goal

Project Goal

Project Goal

Protara required a 90-second mechanism-of-action (MoA) animation as part of its corporate communications strategy. The animation needed to effectively convey the mechanism of TARA-002 to investors, healthcare professionals, and other stakeholders while remaining scientifically accurate and visually engaging. It was intended to support Protara’s broader communication goals and enhance understanding of the therapy.

See full animation.

Protara required a 90-second mechanism-of-action (MoA) animation as part of its corporate communications strategy. The animation needed to effectively convey the mechanism of TARA-002 to investors, healthcare professionals, and other stakeholders while remaining scientifically accurate and visually engaging. It was intended to support Protara’s broader communication goals and enhance understanding of the therapy.

See full animation.

Protara required a 90-second mechanism-of-action (MoA) animation as part of its corporate communications strategy. The animation needed to effectively convey the mechanism of TARA-002 to investors, healthcare professionals, and other stakeholders while remaining scientifically accurate and visually engaging. It was intended to support Protara’s broader communication goals and enhance understanding of the therapy.

See full animation.

3D visualization of T cells and macrophages destroying cancer cells on the inner surface of the bladder

T-cells and macrophages targeting and destroying cancer cells

T-cells and macrophages targeting and destroying cancer cells

T-cells and macrophages targeting and destroying cancer cells

T-cells and macrophages targeting and destroying cancer cells

TARA-002 Being internalized by cell

TARA-002 Being internalized by cell

TARA-002 Being internalized by cell

TARA-002 Being internalized by cell

3D visualization of the TLR2 receptor embedded in the membrane

TLR2 Receptor

TLR2 Receptor

TLR2 Receptor

TLR2 Receptor

"We had a great experience working with the team, who were knowledgeable and professional. We are very pleased with the quality of our medical animation."

"We had a great experience working with the team, who were knowledgeable and professional. We are very pleased with the quality of our medical animation."

"We had a great experience working with the team, who were knowledgeable and professional. We are very pleased with the quality of our medical animation."

"We had a great experience working with the team, who were knowledgeable and professional. We are very pleased with the quality of our medical animation."

Patrick Hsu

Senior Vice President, Investor Relations and
Corporate Affairs at Protara Therapeutics

Senior Vice President,
Investor Relations and
Corporate Affairs at
Protara Therapeutics

Senior Vice President, Investor Relations and
Corporate Affairs at Protara Therapeutics

Close-up visualization of the dendritic cell interacting with the TARA-002 particles

Dendritic cells stimulating the production of pro-inflammatory cytokines

Dendritic cells stimulating the production of pro-inflammatory cytokines

Dendritic cells stimulating the production of pro-inflammatory cytokines

Dendritic cells stimulating the production of pro-inflammatory cytokines

Schematic 3D visualization of the NMIBC tumor

Non-muscle invasive bladder cancer

Non-muscle invasive bladder cancer

Non-muscle invasive bladder cancer

Non-muscle invasive bladder cancer

Streptococcus pyogenes transforming into TARA-002

Streptococcus pyogenes transforming into TARA-002

Streptococcus pyogenes transforming into TARA-002

Streptococcus pyogenes transforming into TARA-002

The Process

The Process

The Process

The Process

Animation type:

Animation type:

Animation type:

3D + High End 3D

3D + High End 3D

3D + High End 3D

Project timline:

Project timline:

Project timline:

7 weeks

7 weeks

7 weeks

Review:

Review:

Review:

3 zoom calls + 7 e-mail feedback sessions

3 zoom calls + 7 e-mail feedback sessions

3 zoom calls + 7 e-mail feedback sessions

Find out which of our 26 scientific animation options works best for investor relations and communications:

Find out which of our 26 scientific animation options works best for investor relations and communications:

Find out which of our 26 scientific animation options works best for investor relations and communications:

To accurately depict TARA-002’s effects, we balanced cellular- and molecular-level visualization while ensuring clarity in storytelling. Our goal was to simplify complex concepts, making the animation accessible to healthcare professionals, investors, and patients. By emphasizing visual storytelling, we translated intricate processes into an engaging, easy-to-follow narrative while maintaining scientific integrity throughout. This included highlighting cellular interactions, using anatomical references, enhancing immune cell visualizations, and blending molecular and cellular perspectives for clarity.


Anatomy Visualization:
To maintain spatial clarity, we incorporated a skeletal model as an anatomical reference, enabling seamless scene transitions and keeping the bladder’s location intuitive for the audience. This approach ensured the animation remained both scientifically accurate and easy to follow.


Enhanced Immune Cell and Molecular Animation:
We expanded our asset library to improve immune cell animations and illustrate how TARA-002 interacts with the immune system. Several scenes combined molecular cut-ins with cellular interactions to highlight key molecular events while maintaining a focus on cellular responses, resulting in a more dynamic and accurate representation of immune effects.


Optimization for Visual Clarity:
To support smooth storytelling and scientific accuracy, we made targeted adjustments to structural dimensions, particularly in scenes blending bacterial cell visuals with molecular interactions. These refinements helped maintain visual consistency and clarity throughout the animation.

To accurately depict TARA-002’s effects, we balanced cellular- and molecular-level visualization while ensuring clarity in storytelling. Our goal was to simplify complex concepts, making the animation accessible to healthcare professionals, investors, and patients. By emphasizing visual storytelling, we translated intricate processes into an engaging, easy-to-follow narrative while maintaining scientific integrity throughout. This included highlighting cellular interactions, using anatomical references, enhancing immune cell visualizations, and blending molecular and cellular perspectives for clarity.


Anatomy Visualization:
To maintain spatial clarity, we incorporated a skeletal model as an anatomical reference, enabling seamless scene transitions and keeping the bladder’s location intuitive for the audience. This approach ensured the animation remained both scientifically accurate and easy to follow.


Enhanced Immune Cell and Molecular Animation:
We expanded our asset library to improve immune cell animations and illustrate how TARA-002 interacts with the immune system. Several scenes combined molecular cut-ins with cellular interactions to highlight key molecular events while maintaining a focus on cellular responses, resulting in a more dynamic and accurate representation of immune effects.


Optimization for Visual Clarity:
To support smooth storytelling and scientific accuracy, we made targeted adjustments to structural dimensions, particularly in scenes blending bacterial cell visuals with molecular interactions. These refinements helped maintain visual consistency and clarity throughout the animation.

Why did we use this
animation type?

Why did we use this
animation type?

Why did we use this
animation type?

A main 3D animation style was chosen to balance cinematic aesthetics with scientific accuracy. By integrating cinematic storytelling techniques—such as strategic lighting, depth of field, and seamless transitions—we enhanced clarity while keeping the animation visually compelling. Focusing on cellular interactions allowed for a more intuitive understanding of TARA-002’s mechanism while maintaining scientific rigor.

A main 3D animation style was chosen to balance cinematic aesthetics with scientific accuracy. By integrating cinematic storytelling techniques—such as strategic lighting, depth of field, and seamless transitions—we enhanced clarity while keeping the animation visually compelling. Focusing on cellular interactions allowed for a more intuitive understanding of TARA-002’s mechanism while maintaining scientific rigor.

A main 3D animation style was chosen to balance cinematic aesthetics with scientific accuracy. By integrating cinematic storytelling techniques—such as strategic lighting, depth of field, and seamless transitions—we enhanced clarity while keeping the animation visually compelling. Focusing on cellular interactions allowed for a more intuitive understanding of TARA-002’s mechanism while maintaining scientific rigor.

Outcome:

Outcome:

Outcome:

The final medical animation effectively conveyed TARA-002’s mechanism of action, striking a balance between scientific precision and accessibility. By integrating cinematic visuals with clear explanations, the animation became a powerful tool for investor relations, corporate presentations, and industry events. Completing the project within a fixed timeline ensured the animation was available for a key industry event, maximizing its impact across investor presentations and corporate communications. This project highlights how strategic animation techniques can enhance engagement and understanding through medical communication solutions for biotech, demonstrating the value of well-structured visual storytelling.

The final medical animation effectively conveyed TARA-002’s mechanism of action, striking a balance between scientific precision and accessibility. By integrating cinematic visuals with clear explanations, the animation became a powerful tool for investor relations, corporate presentations, and industry events. Completing the project within a fixed timeline ensured the animation was available for a key industry event, maximizing its impact across investor presentations and corporate communications. This project highlights how strategic animation techniques can enhance engagement and understanding through medical communication solutions for biotech, demonstrating the value of well-structured visual storytelling.

Full animation

Full animation

Full animation

Case Study Animation

Case Study Animation

Case Study Animation

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/10

“Fantastic team to partner with throughout the entire process. Excellent output and management!”

Pádraig Moran

Global Marketing Director, Pfizer

/10

"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"

Noel Kurdi

VP, Investor Relations, Apogee Therapeutics

/10

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

Bob Nichols

VP, Corp Dev, Revolution Medicines

/10

“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.

Rosana Kapeller

President, CEO and co-founder, ROME Therapeutics

/10

“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”

Paul Peter Tak

President, CEO and Board Director, Candel Therapeutics

/10

“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

Michael Zasloff

CSO, Enterin

/10

“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Guru Reddy

Vice President, R&D, Unicycive Therapeutics

/10

"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."

Lynnea Waters

Director, Scientific Communications, Apogee Therapeutics

/10

“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

Ravi Moorthy

VP, Head of Communications, Scorpion Therapeutics

/10

“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

John Hanna

CEO, Apton

/10

“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

Patrick Ritschel

CEO, Atsena Therapeutics

/10

“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Blake Aronson

Program Manager, ACS

/10

“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”

Jan Smith

CSO, Biology, Revolution Medicines

/10

"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"

Josh Cirulli

VP, Medical Affairs, Apogee Therapeutics

/10

“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

Anirvan Ghosh

CEO, UNITY Biotechnology

/10

"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."

Patrick Hsu

Co-Founder, Arc Institute · Assistant Professor, UC Berkeley

/10

"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."

Jen Do, Associate Director, External Sci Comm, AbbVie

Jen Do

Associate Director, External Sci Comm, AbbVie

/10

"Excellent work by the Visual Science team!"

Miguel Sobral

Associate Director, BD&Strategy, Apogee Therapeutics

/10

"Excellent work and project management."

Daniel Martins, Scientific Director, AbbVie

Daniel Martins

Scientific Director, AbbVie

/10

"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."

Aparna Shetty, Lead, Scientific Communications and Content, Astellas

Aparna Shetty

Lead, Scientific Communications and Content, Astellas

/10

"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."

Taylor Schreiber, CEO, Shattuck Labs, Inc.

Taylor Schreiber

CEO, Shattuck Labs, Inc.

/10

"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."

Edmund Doherty - Vice President of Medical Affairs | Clinical Strategy | Global People Leader, Atsena Therapeutics

Edmund Doherty

Vice President of Medical Affairs, Atsena Therapeutics

/10

"Very responsive and efficient. Thank you!"

Brian Padden, Asset Strategy Leader, AbbVie

Brian Padden

Asset Strategy Leader, AbbVie

Contact us

Contact us

/10

“Fantastic team to partner with throughout the entire process. Excellent output and management!”

Pádraig Moran

Global Marketing Director, Pfizer

/10

"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"

Noel Kurdi

VP, Investor Relations, Apogee Therapeutics

/10

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

Bob Nichols

VP, Corp Dev, Revolution Medicines

/10

“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.

Rosana Kapeller

President, CEO and co-founder, ROME Therapeutics

/10

“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”

Paul Peter Tak

President, CEO and Board Director, Candel Therapeutics

/10

“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

Michael Zasloff

CSO, Enterin

/10

“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Guru Reddy

Vice President, R&D, Unicycive Therapeutics

/10

"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."

Lynnea Waters

Director, Scientific Communications, Apogee Therapeutics

/10

“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

Ravi Moorthy

VP, Head of Communications, Scorpion Therapeutics

/10

“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

John Hanna

CEO, Apton

/10

“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

Patrick Ritschel

CEO, Atsena Therapeutics

/10

“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Blake Aronson

Program Manager, ACS

/10

“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”

Jan Smith

CSO, Biology, Revolution Medicines

/10

"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"

Josh Cirulli

VP, Medical Affairs, Apogee Therapeutics

/10

“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

Anirvan Ghosh

CEO, UNITY Biotechnology

/10

"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."

Patrick Hsu

Co-Founder, Arc Institute · Assistant Professor, UC Berkeley

/10

"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."

Jen Do, Associate Director, External Sci Comm, AbbVie

Jen Do

Associate Director, External Sci Comm, AbbVie

/10

"Excellent work by the Visual Science team!"

Miguel Sobral

Associate Director, BD&Strategy, Apogee Therapeutics

/10

"Excellent work and project management."

Daniel Martins, Scientific Director, AbbVie

Daniel Martins

Scientific Director, AbbVie

/10

"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."

Aparna Shetty, Lead, Scientific Communications and Content, Astellas

Aparna Shetty

Lead, Scientific Communications and Content, Astellas

/10

"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."

Taylor Schreiber, CEO, Shattuck Labs, Inc.

Taylor Schreiber

CEO, Shattuck Labs, Inc.

/10

"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."

Edmund Doherty - Vice President of Medical Affairs | Clinical Strategy | Global People Leader, Atsena Therapeutics

Edmund Doherty

Vice President of Medical Affairs, Atsena Therapeutics

/10

"Very responsive and efficient. Thank you!"

Brian Padden, Asset Strategy Leader, AbbVie

Brian Padden

Asset Strategy Leader, AbbVie

Contact us

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

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Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor, New York, NY 10281, USA

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo
Visual Science Logo