Scientifically accurate 3D model and animation of HIV

We created this 3D model and visualization of the HIV viral particle in 2009. In 2010, it was awarded first place and named Best Scientific Visualization at the Science and Engineering Visualization Challenge (SEVC), a competition organized by Science magazine and the National Science Foundation.


Since then, it has appeared on the covers of special issues of Nature Medicine and the International AIDS Vaccine Initiative (IAVI) Report, as well as in influential textbooks such as Vaccines and Principles of Virology. It has also been featured in The New York Times, Cell Picture Show by Cell Press, National Geographic, Wired, Popular Science, and other publications. The model received positive feedback from Nobel Prize winners, including Françoise Barré-Sinoussi.

We created this 3D model and visualization of the HIV viral particle in 2009. In 2010, it was awarded first place and named Best Scientific Visualization at the Science and Engineering Visualization Challenge (SEVC), a competition organized by Science magazine and the National Science Foundation.


Since then, it has appeared on the covers of special issues of Nature Medicine and the International AIDS Vaccine Initiative (IAVI) Report, as well as in influential textbooks such as Vaccines and Principles of Virology. It has also been featured in The New York Times, Cell Picture Show by Cell Press, National Geographic, Wired, Popular Science, and other publications. The model received positive feedback from Nobel Prize winners, including Françoise Barré-Sinoussi.

Project Goal

Create the most scientifically accurate and detailed 3D model of the HIV particle in atomic resolution.

HIV viral particle visualization with a cut-out showing internal capsid structures
HIV viral particle visualization with a cut-out showing internal capsid structures
HIV viral particle visualization with a cut-out showing internal capsid structures

HIV whole model visualization

HIV viral particle surface with ENV glycoproteins
HIV viral particle surface with ENV glycoproteins
HIV viral particle surface with ENV glycoproteins

Surface proteins on the HIV particle

Envelope and capsid of the HIV particle

“Congratulations on your very successful 3D HIV model!”

“Congratulations on your very successful 3D HIV model!”

Prof. Françoise Barré-Sinoussi
Prof. Françoise Barré-Sinoussi
Prof. Françoise Barré-Sinoussi

Nobel Prize in Medicine 2008, Pasteur Institute, Paris, France

Nobel Prize in Medicine 2008, Pasteur Institute, Paris, France

“Based on our experience, we highly recommend Visual Science as a reliable, trustworthy partner with excellent scientific, artistic and organizational expertise.”

“Based on our experience, we highly recommend Visual Science as a reliable, trustworthy partner with excellent scientific, artistic and organizational expertise.”

Alan Bernstein
Alan Bernstein
Alan Bernstein

Executive Director

Global HIV Vaccine Enterprise

Executive Director

Global HIV Vaccine Enterprise

Nature Medicine cover with the HIV visualization made by Visual Science
Nature Medicine cover with the HIV visualization made by Visual Science
Nature Medicine cover with the HIV visualization made by Visual Science

Nature Medicine special issue cover

Close-up view of the HIV capsid with genetic material visible inside
Close-up view of the HIV capsid with genetic material visible inside
Close-up view of the HIV capsid with genetic material visible inside

The particle core

Envelope proteins on the HIV surface

The Process

Animation type:

High-end 3D based on science grade molecular simulations

Project timline:

16 weeks

Team:

Find out which of our 7 scientific animation types and 20 subtypes work best for your project

This model summarizes results from more than 100 scientific publications published prior to 2009. Our team spent many weeks collecting and analyzing data, consulting with virologists, and assembling and refining the molecular structures of HIV components. None of the currently available scientific methods allow for obtaining an image of the entire virus particle at atomic resolution.

Nevertheless, hundreds of studies by researchers around the world have shed light on the structure and morphology of virion components and their interactions, making the creation of this model possible.

The first-ever molecular animation based on science-grade molecular simulations:

This complex and highly resource-intensive project was the first high-end molecular visualization we produced, and it set standards not only for our team but also for many of our colleagues in the industry. The depicted spatial configurations of 17 different viral and cellular proteins present in the HIV particle are strictly consistent with known 3D structures.

The viral membrane in the model includes approximately 160,000 lipid molecules of eight different types, in proportions consistent with those found in the HIV particle.

Full animation

Contact us

Contact us

Contact us

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

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© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

London

44 20 3734-2517

Address

200 Vesey Street, 24th floor, New York, NY 10281, USA

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

Visual Science Logo
Visual Science Logo
Visual Science Logo