UNI-494 Drug: Mechanism of Action
Client:
Unicycive Therapeutics is focused on development of approaches to treat kidney diseases. One of the companies key technologies targets mitochondrial damage or dysfunction that contributes critically to the pathogenesis of various kidney diseases.
Unicycive Therapeutics is focused on development of approaches to treat kidney diseases. One of the companies key technologies targets mitochondrial damage or dysfunction that contributes critically to the pathogenesis of various kidney diseases.
NAS: UNCY
NAS: UNCY
Client:
Project Goal
Create a scientific 3D explainer animation for investor communications and the client website to demonstrate the mechanism of action of the company's key drug technology.
Normal mitochondrion
Nicorandil bound to a K+-sensitive ATP channel
UNI-494 activation by an esterase
“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
VP of Preclinical R&D
Closed MPT-pore and K+-sensitive ATP channel
Nicorandil molecule in the cytoplasm
Swelling of a mitochondrion
The Process
Animation type:
Main 3D
Project timline:
9 weeks
Review:
3 zoom calls + 2 e-mail feedback sessions
Team:
Find out which of our 26 scientific animation options works best for investor relations and communications in 2023:
For this project, we employed our effective "5:4" production process, which has been refined over hundreds of projects. It consists of five production steps — starting with the script and dynamic storyboards, progressing to science-grade molecular modeling and animation visualization, and finally post-production — and four intermediate review steps.
Between the production stages, we send all crucial information to our clients for review, giving them complete control over the final product. This approach significantly limits the average client time commitment, totaling only several hours for review and communication with the Visual Science team.
Our production and account management teams' deep scientific expertise prevents our clients from having to give detailed instructions or spend hours explaining their requirements to achieve industry-leading animation quality and scientific accuracy.
Why did we use this
animation type?
For this MoA animation, we utilized our "Main 3D" animation type, which is the gold standard for such projects. It's one of the most popular options of the four main types and 25 variations we offer, designed to cater to various audiences, business goals, company stages, timeframes, and budgets.
We visualized the UNI-494 mechanism of action without going into the details of complex molecular interactions. This approach allowed us to develop a short, comprehensive, and well-balanced animation that provides an essential overview of the topic in an eye-catching format, effectively holding the audience's attention.
Full animation
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
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Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
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Beautiful work that is detailed and thoughtful. Great final output.”
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10/10
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We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
CEO, Atsena Therapeutics
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
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CEO, Atsena Therapeutics
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
Program Manager, American Chemical Society
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
CEO, Apton Biosystems
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Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
VP, Head of Communications, Scorpion Tx
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The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”
Science Content Lead, Dewpoint Tx
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
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We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”
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We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”
President & CEO, ROME Tx
10/10
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Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
VP, Corp Dev, Revolution Medicines
10/10
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We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
CEO, Atsena Therapeutics
10/10
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
Program Manager, American Chemical Society
10/10
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
CEO, Apton Biosystems
9/10
“
Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
VP, Head of Communications, Scorpion Tx
7/10
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The structural biology models from Visual Science are stunning! Visual Science implemented our guidelines into beautiful scientific imagery for our website and scientific slide decks.”
Science Content Lead, Dewpoint Tx
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
Vice President, R&D, Unicycive Tx
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We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”
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The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”
CEO, UNITY Biotechnology
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Beautiful work that is detailed and thoughtful. Great final output.”
Sr. Comms & IR Associate, Candel Tx
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“
We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”
President & CEO, ROME Tx
10/10
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Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
VP, Corp Dev, Revolution Medicines
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We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”
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The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”
Program Manager, American Chemical Society
10/10
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Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”
CEO, Apton Biosystems
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Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”
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I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”
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We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.”
President & CEO, ROME Tx
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Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”
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Contact us
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.
We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.
© 2026, Visual Science. All rights reserved.
