Modified IL-2-based cancer immunotherapy drug: 3D MoA

Client:

Neoleukin logo
Neoleukin logo

Neoleukin is a pioneer in de novo protein development, leveraging computational methods to create new therapies. Neoleukin is creating next generation immunotherapies using breakthrough de novo protein design technology. Neoleukin uses natural protein complexes as inspiration to develop custom designed proteins with superior pharmaceutical properties.

Neoleukin is a pioneer in de novo protein development, leveraging computational methods to create new therapies. Neoleukin is creating next generation immunotherapies using breakthrough de novo protein design technology. Neoleukin uses natural protein complexes as inspiration to develop custom designed proteins with superior pharmaceutical properties.

Client:

Neoleukin logo

Project goal

Create an MoA animation presenting the company's lead program for investor relations.

IL-2 receptor structure

Simplified 3D visualization of the surface of an immune cells with IL-2 molecules bound to the receptors

Surface of the off-target cell

Modified IL-2 molecules with PEG molecule bound

NL-201 molecule conjugated with PEG

“Visual Science created a vibrant animation that will help us in our investor relations and communications efforts, illustrating our de novo protein design approach to developing novel therapies for patients.”

“Visual Science created a vibrant animation that will help us in our investor relations and communications efforts, illustrating our de novo protein design approach to developing novel therapies for patients.”

Robert Ho photo

Chief Financial Officer

Neoleukin Therapeutics

Seattle, WA

Chief Financial Officer

Neoleukin Therapeutics

Seattle, WA

3D visualization of CD8 positive T cell and and off-target immune cell

CD8 T-cell and an off-target cell

3D visualization of interleukin 2 molecule in the ribbon and surface representation

Native interleukin-2 molecule

NL-201 molecule

The Process

Animation type:

Deck 3D + 3D

Project timline:

8 weeks

Review:

3 zoom calls + 5 e-mail feedback sessions

Find out which of our 26 scientific animation options works best for investor relations and communications:

Neoleukin's goal was to effectively communicate the advantages of their de novo protein design program to their investors and partners during the JPM healthcare conference. In support, we created a set of informative and eye-catching illustrations for the client's corporate deck, as well as a 3D medical animation for use both at the conference and on the Neoleukin website.

With only one month before the conference, the timeline was too tight to allow creation of a complete High-end 3D animation. Instead, we planned the development process to allow design of a set of 3D illustrations depicting the technology's key elements first, before then completing the animation.

Why did we use this
animation type?

Neoleukin Theraputics develops de novo protein drugs — a field of development tightly associated with computational biology and other methods Visual Science uses to create scientifically accurate models. Since we pioneered this approach in 2008, our high-end animations and molecular visualizations have remained unique on the market in terms of scientific accuracy and level of detail. This has allowed us to build the most accurate and detailed models of a range of human viruses, from HIV and influenza, to Ebola and Zika. However, high-end animations can only be created using scientific-grade molecular modeling and simulation, meaning that this approach's only downside is the amount of resources and time required.

In this case, since our client's time was limited, we used the high-end style only for the most crucial elements of the story, and applied less time-consuming regular 3D modeling for the rest of the animation. Our combined approach in this case enabled us to produce a superior-quality animation within a timeline more akin to those for much less accurate and eye-catching 3D animations, supporting scientific communication for biotech.

Full animation

Case Study Animation

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/10

“Fantastic team to partner with throughout the entire process. Excellent output and management!”

Pádraig Moran

Global Marketing Director, Pfizer

/10

"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"

Noel Kurdi

VP, Investor Relations, Apogee Therapeutics

/10

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

Bob Nichols

VP, Corp Dev, Revolution Medicines

/10

“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.

Rosana Kapeller

President, CEO and co-founder, ROME Therapeutics

/10

“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”

Paul Peter Tak

President, CEO and Board Director, Candel Therapeutics

/10

“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

Michael Zasloff

CSO, Enterin

/10

“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Guru Reddy

Vice President, R&D, Unicycive Therapeutics

/10

"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."

Lynnea Waters

Director, Scientific Communications, Apogee Therapeutics

/10

“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

Ravi Moorthy

VP, Head of Communications, Scorpion Therapeutics

/10

“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

John Hanna

CEO, Apton

/10

“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

Patrick Ritschel

CEO, Atsena Therapeutics

/10

“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Blake Aronson

Program Manager, ACS

/10

“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”

Jan Smith

CSO, Biology, Revolution Medicines

/10

"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"

Josh Cirulli

VP, Medical Affairs, Apogee Therapeutics

/10

“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

Anirvan Ghosh

CEO, UNITY Biotechnology

/10

"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."

Patrick Hsu

Co-Founder, Arc Institute · Assistant Professor, UC Berkeley

/10

"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."

Jen Do, Associate Director, External Sci Comm, AbbVie

Jen Do

Associate Director, External Sci Comm, AbbVie

/10

"Excellent work by the Visual Science team!"

Miguel Sobral

Associate Director, BD&Strategy, Apogee Therapeutics

/10

"Excellent work and project management."

Daniel Martins, Scientific Director, AbbVie

Daniel Martins

Scientific Director, AbbVie

/10

"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."

Aparna Shetty, Lead, Scientific Communications and Content, Astellas

Aparna Shetty

Lead, Scientific Communications and Content, Astellas

/10

"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."

Taylor Schreiber, CEO, Shattuck Labs, Inc.

Taylor Schreiber

CEO, Shattuck Labs, Inc.

/10

"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."

Edmund Doherty - Vice President of Medical Affairs | Clinical Strategy | Global People Leader, Atsena Therapeutics

Edmund Doherty

Vice President of Medical Affairs, Atsena Therapeutics

/10

"Very responsive and efficient. Thank you!"

Brian Padden, Asset Strategy Leader, AbbVie

Brian Padden

Asset Strategy Leader, AbbVie

Contact us

Contact us

/10

“Fantastic team to partner with throughout the entire process. Excellent output and management!”

Pádraig Moran

Global Marketing Director, Pfizer

/10

"Visual Science produced an excellent website with incredible imagery, working in a professional, efficient manner to create a stunning final product! They were engaged through every step of the process and were attentive to the ideas we had in mind for our website. They continue to work with us on all updates and requests in a timely and helpful manner!"

Noel Kurdi

VP, Investor Relations, Apogee Therapeutics

/10

“Excellent scientific partner and first class imagery. This team runs a tight ship and the process is clear. The tech and final product are first rate.”

Bob Nichols

VP, Corp Dev, Revolution Medicines

/10

“We were impressed by the Visual Science team’s ability to use exact protein structures to depict complex mechanisms in <90 seconds. The visuals are beautiful and tell a clear story.

Rosana Kapeller

President, CEO and co-founder, ROME Therapeutics

/10

“Visual Science has a unique ability to communicate complex science with both accuracy and visual impact. Their team combines scientific understanding with creativity, helping bring sophisticated biomedical concepts to life.”

Paul Peter Tak

President, CEO and Board Director, Candel Therapeutics

/10

“We were impressed by the scientific sophistication of the Visual Science team and their skill in capturing the concepts we wanted to communicate. The final video was exceptional.”

Michael Zasloff

CSO, Enterin

/10

“I was very impressed with scientific knowledge of the Visual Science team, which led to a fantastic visualization of the MOA of our drug. Attention to scientific details was extraordinary.”

Guru Reddy

Vice President, R&D, Unicycive Therapeutics

/10

"Visual Science was a great partner in the development and delivery of scientific animations; the combination of their understanding of the science and their artistic expertise resulted in a visually stunning and impactful video."

Lynnea Waters

Director, Scientific Communications, Apogee Therapeutics

/10

“Visual Science is a fantastic partner, capable of rendering the most complex science in compelling ways. They understood the science, and their production was excellent.”

Ravi Moorthy

VP, Head of Communications, Scorpion Therapeutics

/10

“Visual Science team has just the right blend of scientific acumen and digital animation expertise to pull off these challenging projects.”

John Hanna

CEO, Apton

/10

“We are very pleased with Visual Science — they are a very responsive group to work with and the final product is exactly what we had envisioned.”

Patrick Ritschel

CEO, Atsena Therapeutics

/10

“The scientific expertise really showed in the discussions and final products. Everybody was responsive and great to work with, and the animations were both engaging and accurate!”

Blake Aronson

Program Manager, ACS

/10

“The creativity, scientific competency and professionalism of the Visual Science team not only enabled the generation of high-quality images, but also made it a pleasure to work with them.”

Jan Smith

CSO, Biology, Revolution Medicines

/10

"Incredible animations that really help bring our science to life. I strongly recommend Visual Science!"

Josh Cirulli

VP, Medical Affairs, Apogee Therapeutics

/10

“The quality of the work from Visual Science was outstanding. They provide a bespoke service that was responsive to our requests and I would recommend them highly.”

Anirvan Ghosh

CEO, UNITY Biotechnology

/10

"We were impressed with the Visual Science team's attention to detail and ability to extract key messages out of a complex scientific story. Their deep understanding of the science enabled them to turn our cryo-EM structures into a beautiful visual that shows the key aspects of the bridge recombination mechanism."

Patrick Hsu

Co-Founder, Arc Institute · Assistant Professor, UC Berkeley

/10

"The Visual Science team did an outstanding job delivering beautiful MOA videos for us. The animations and attention to detail were exceptional, and their flexibility throughout the process made a huge difference."

Jen Do, Associate Director, External Sci Comm, AbbVie

Jen Do

Associate Director, External Sci Comm, AbbVie

/10

"Excellent work by the Visual Science team!"

Miguel Sobral

Associate Director, BD&Strategy, Apogee Therapeutics

/10

"Excellent work and project management."

Daniel Martins, Scientific Director, AbbVie

Daniel Martins

Scientific Director, AbbVie

/10

"Visual Science produces high quality animations to support our unique science with agility and speed. I do value their partnership and look forward to working on more projects with them."

Aparna Shetty, Lead, Scientific Communications and Content, Astellas

Aparna Shetty

Lead, Scientific Communications and Content, Astellas

/10

"The VS team was outstanding to work with on this project. From the outset, the level of communication, organization, and attention to detail was exceptional. The VS team moved a complication MoA project forward on-schedule, with scientific rigor, and the result was a beautifully composed video that distilled complex biology in a visually accurate way. I highly recommend this team."

Taylor Schreiber, CEO, Shattuck Labs, Inc.

Taylor Schreiber

CEO, Shattuck Labs, Inc.

/10

"Thank you very much for such a great deliverable on a very tight timeline. I have been doing things like this for a long time and your incorporation of the Atsena insights to this with a very fast turnaround is very much appreciated and impressive."

Edmund Doherty - Vice President of Medical Affairs | Clinical Strategy | Global People Leader, Atsena Therapeutics

Edmund Doherty

Vice President of Medical Affairs, Atsena Therapeutics

/10

"Very responsive and efficient. Thank you!"

Brian Padden, Asset Strategy Leader, AbbVie

Brian Padden

Asset Strategy Leader, AbbVie

Contact us

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

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© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor, New York, NY 10281, USA

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo

Visual Science is an award-winning medical animation and digital scientific communications company, trusted by leading biotech and pharmaceutical organizations since 2007, including J&J, Pfizer, Novartis, Roche, Takeda, Gilead, AbbVie, and 100+ others.

We specialize in science-grade MoA and MoD videos, medical animation, and scientific storytelling, as well as digital and AI-driven solutions for Medical Affairs, marketing, corporate communications, and investor relations.

Contacts

US toll-free

1 888 374-16-95

NY

1 516 340-37-30

Address

200 Vesey Street, 24th floor,
New York, NY 10281, USA

Social networks

LinkedIn Logo
Vimeo Logo

© 2026, Visual Science. All rights reserved.

Privacy policy & Cookie policy

  • The Telly Awards logo
  • Hermes Creative Awards Logo
  • The Communicator Awards logo
  • National Science Foundation logo
  • Science Magazine Logo
  • Viddy Awards Logo
Visual Science Logo